MODAPLEX NRAS Mutation Kit

Detect 16 NRAS mutations with high sensitivity in 4 hours

Features

  • Detect 16 pathogenic NRAS mutations according to latest research developments
  • Obtain precise insights using a test developed with colorectal cancer samples
  • Fast and easy analysis

The MODAPLEX NRAS Mutation Kit is a qualitative and comprehensive PCR-based multiplex assay for the detection of 16 mutations within the NRAS gene in human DNA derived from formalin-fixed, paraffin-embedded (FFPE) samples using the MODAPLEX instrument. The assay must be used by qualified and trained personnel in a professional laboratory environment only. Results are intended solely for research use and not for diagnostic procedures.

Biomarker

G12:

G12A  c.35G>C

G12C  c.34aG>T

G12D  c.35G>A

G12R  c.34G>C

G12S  c.34G>A

G12V  c.35G>T

G12:

G13C c.37G>T

G13D c.38G>A

G13R c.37G>C

G13V c.38G>T

Q61:

Q61H c.183A>C,  c.183A>T

Q61K c.181C>A

Q61L c.182A>T

Q61P c.182A>C

Q61R  c.182A>G

Product Specifications

  • Panel
  • 16 mutations
  • Reactions
  • 2 multiplex PCR reactions per sample
  • Internal controls
  • 1 (within NRAS gene)
  • PCR controls
  • 2 external controls included (PC,NTC), 2 internal well specific amplification controls  
  • Sample input
  • ~ 2x10 ng gDNA (FFPE)
  • Turnaround time
  • ~ 4 h excluding nucleic acid preparation (including data analysis)
  • Detection
  • Qualitative
  • To be used with
  • MODAPLEX instrument
  • Data analysis
  • MODAPLEX Reporter software

Resources

Instructions for Use / Handbooks
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Instructions for Use / Handbooks
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Safety Data Sheets / Non-Hazardous Statements
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Non Hazardous Statements
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Technical Information
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Ordering Information

MODAPLEX NRAS Mutation Kit

Size: 50 reactions
Cat. No: Coming soon
Status: RUO*


*RUO - Research Use Only products must be validated by the customer with clinically relevant material for diagnostic purposes.

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