Now Available: ExaccType® ESR1 dPCR Kit

New from BIOTYPE: Sensitive ESR1 Mutation Detection with the ExaccType^® ESR1 dPCR Kit

In hormone receptor-positive breast cancer research, ESR1 mutations are critical markers for understanding tumor evolution, liquid biopsy dynamics, and acquired endocrine resistance.

Today, we are introducing a powerful tool to advance this research: the ExaccType^® ESR1 dPCR Kit. Built for sensitive detection of low-frequency variants, it targets 11 ESR1 mutations in the ligand-binding domain, including key hotspots like D538G and Y537S.

Key Highlights:

• Detection of 11 ESR1 mutations across exons 5, 7, and 8
• Demonstrated detection at 0.1% mutant allele frequency (MAF)
• Analysis of DNA, including plasma-derived cfDNA
• Wild-type suppression for selective mutation detection
• Compatibility with standard probe-based digital PCR platforms
• Results in less than 3 hours, with less than 1 hour of hands-on time

Supporting Translational Oncology

The ExaccType^® ESR1 dPCR Kit supports oncology and translational research, including liquid biopsy studies of low-frequency ESR1 mutations. At BIOTYPE, we combine reliable molecular tools with expert support so your laboratory can focus on the science.